Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026973 | 1.00 | CYP2C9 (0.47) | CYP2C9MAPTNPY5RKDM1AMAOA | |
| SCHEMBL8420749 | 0.94 | MAPT (0.52) | CYP2C9MAPTNPY5RPTGS2SMN1; SMN2 | |
| SCHEMBL8421776 | 0.94 | KDM1A (0.47) | MAPTKDM1AMAOAPTGS2GAA | |
| SCHEMBL8641119 | 0.93 | AURKA (0.46) | CYP2C9MAPTKDM1AMAOAPTGS2 | |
| SCHEMBL8421504 | 0.92 | MALT1 (0.40) | CYP2C9MAPTNPY5RKDM1AMAOA | |
| SCHEMBL8423750 | 0.90 | KDM1A (0.46) | CYP2C9MAPTNPY5RKDM1AMAOA | |
| SCHEMBL8422282 | 0.90 | KDM1A (0.43) | CYP2C9MAPTNPY5RKDM1AMAOA | |
| SCHEMBL8424131 | 0.89 | KDM1A (0.41) | MAPTNPY5RKDM1AMAOAPTGS2 | |
| SCHEMBL8421856 | 0.89 | KDM1A (0.41) | MAPTNPY5RKDM1AMAOAPTGS2 | |
| SCHEMBL8422285 | 0.88 | MAPT (0.43) | MAPTNPY5RKDM1AMAOAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |