Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026973 | 0.94 | CYP2C9 (0.47) | MAPTCYP2C9NPY5RPTGS2SMN1; SMN2 | |
| SCHEMBL8422295 | 0.94 | CYP2C9 (0.47) | MAPTCYP2C9NPY5RPTGS2SMN1; SMN2 | |
| SCHEMBL8422371 | 0.90 | MAPT (0.45) | MAPTCYP2C9NPY5RALDH1A1MEN1 | |
| SCHEMBL8422134 | 0.87 | MAPT (0.51) | MAPTCYP2C9NPY5RPTGS2ALDH1A1 | |
| SCHEMBL8421857 | 0.87 | UQCRB (0.43) | MAPTCYP2C9NPY5RPTGS2MEN1 | |
| SCHEMBL8421776 | 0.87 | KDM1A (0.47) | MAPTPTGS2MEN1KMT2AKDM4E | |
| SCHEMBL8422144 | 0.87 | MAPT (0.45) | MAPTCYP2C9NPY5RPTGS2ALDH1A1 | |
| SCHEMBL8423873 | 0.87 | MAPT (0.47) | MAPTCYP2C9NPY5RALDH1A1MEN1 | |
| SCHEMBL8420265 | 0.86 | NPY5R (0.51) | MAPTCYP2C9NPY5RPTGS2ALDH1A1 | |
| SCHEMBL8420779 | 0.86 | ALDH1A1 (0.41) | MAPTCYP2C9NPY5RPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |