Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423750 | 0.96 | KDM1A (0.46) | KDM1AMAOAKAT6AMCL1CYP2C9 | |
| SCHEMBL8421504 | 0.91 | MALT1 (0.40) | KDM1AMAOAPTGS2CYP2C9MAPT | |
| SCHEMBL8420103 | 0.90 | PTGS2 (0.45) | KDM1AMAOAKAT6APTGS2MAPT | |
| SCHEMBL8422295 | 0.90 | CYP2C9 (0.47) | KDM1AMAOAPTGS2CYP2C9MAPT | |
| SCHEMBL8026973 | 0.90 | CYP2C9 (0.47) | KDM1AMAOAPTGS2CYP2C9MAPT | |
| SCHEMBL8641119 | 0.90 | AURKA (0.46) | KDM1AMAOAKAT6APTGS2CYP2C9 | |
| SCHEMBL8421776 | 0.89 | KDM1A (0.47) | KDM1AMAOAKAT6APTGS2MAPT | |
| SCHEMBL8419964 | 0.87 | MAPT (0.42) | KDM1AMAOAKAT6APTGS2MAPT | |
| SCHEMBL8424142 | 0.87 | KAT6A (0.47) | KDM1AMAOAKAT6AAURKAALDH1A1 | |
| SCHEMBL8421734 | 0.87 | KDM1A (0.43) | KDM1AMAOAKAT6AMAPTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |