Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420177 | 0.87 | HSD17B10 (0.38) | MEN1KMT2AL3MBTL1F2HSD17B10 | |
| SCHEMBL7811676 | 0.65 | F2 (0.52) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7825334 | 0.65 | F2 (0.50) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7847492 | 0.63 | F2 (0.45) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7825524 | 0.63 | F2 (0.60) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7819612 | 0.61 | F2 (0.51) | F2SETDB1PRSS1PRSS2PRSS3 | |
| SCHEMBL658361 | 0.60 | KDM4E (0.70) | MEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL8418937 | 0.59 | — | — | |
| SCHEMBL7817160 | 0.59 | F2 (0.41) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7824021 | 0.58 | F2 (0.39) | F2PRSS1PRSS2PRSS3MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866573-A | Pyrazinone thrombin inhibitors | MERCK & CO., INC. (US) | 1999-02-02 | — | — | US | disclosed |