Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 18/20 | 0.53 |
| ▸ | CA2 | P00918 | 18/20 | 0.53 |
| ▸ | CA7 | P43166 | 6/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA3 | P07451 | 3/20 | 0.53 |
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | CA6 | P23280 | 3/20 | 0.53 |
| ▸ | CA5A | P35218 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630225 | 0.83 | CA1 (0.65) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL31069942 | 0.80 | KDM4E (0.44) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL9630166 | 0.74 | CA1 (0.50) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL11559995 | 0.74 | MAPT (0.53) | MAPTCA1CA2CA7CA13 | |
| SCHEMBL9630198 | 0.73 | CA1 (0.73) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL9630937 | 0.73 | CA1 (0.48) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL13687260 | 0.72 | CA1 (0.66) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL9630165 | 0.72 | CA1 (0.47) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL10382771 | 0.71 | CA1 (0.44) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL9632120 | 0.71 | KDM4E (0.48) | KDM4ELMNAGLAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110538160-A | indapamide tablet and preparation method thereof | SUICHENG PHARMACEUTICAL CO LTD | 2019-12-06 | — | — | CN | disclosed |
| CN-101717359-A | Method for synthesizing indapamide | BEIJING CHENGYU PHARMACEUTICAL | 2010-06-02 | — | — | CN | disclosed |
| EP-0462016-B1 | Process for the industrial preparation of 4-chloro-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl) benzamide | ADIR (FR) | 1999-09-29 | — | — | EP | disclosed |
| EP-0462017-B1 | PROCESS FOR THE INDUSTRIAL PREPARATION OF 3-SULFAMOYL-4-CHLORO-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)BENZAMIDE FROM 2,3-DIHYDRO-2-METHYL-1H-INDOLE AND HYDROXYLAMINE-O-SULFONIC ACID | ADIR ET COMPAGNIE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-5110946-A | PREPARATION OF 4-CHLORO-3-SULPHAMOYL-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)-BENZAMIDE FROM 2,3-DIHYDRO-2-METHYL-1H-INDOLE AND HYDROXYLAMINE-O-SULPHONIC ACID | ADIR ET COMPAGNIE (FR) | 1992-05-05 | — | — | US | disclosed |
| US-5101040-A | PROCESS FOR THE INDUSTRIAL PREPARATION OF 4-CHLORO-3-SULFAMOYL-N-(2,3-DIHYDRO-2-METHYL-1H-INDOL-1-YL)BENZAMIDE | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |
| EP-0462016-A1 | Process for the industrial preparation of 4-chloro-3-sulfamoyl-N-(2,3-dihydro-2-methyl-1H-indol-1-yl) benzamide | ADIR ET COMPAGNIE (FR) | 1991-12-18 | — | — | EP | disclosed |
| EP-0462017-A1 | Process for the industrial preparation of 3-sulfamoyl-4-chloro-N-(2,3-dihydro-2-methyl-1H-indol-1-yl)benzamide from 2,3-dihydro-2-methyl-1H-indole and hydroxylamine-O-sulfonic acid | ADIR ET COMPAGNIE (FR) | 1991-12-18 | — | — | EP | disclosed |