Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA1 | P00915 | 11/20 | 0.43 |
| ▸ | CA7 | P43166 | 11/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 11/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA3 | P07451 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 4/20 | 0.43 |
| ▸ | CA6 | P23280 | 4/20 | 0.43 |
| ▸ | CA5A | P35218 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422346 | 0.80 | KDM4E (0.53) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL31069940 | 0.77 | KDM4E (0.52) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL31069941 | 0.76 | CA2 (0.66) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL6480184 | 0.69 | MEN1 (0.57) | KDM4ELMNAHSD17B10ALDH1A1GAA | |
| SCHEMBL6480068 | 0.69 | MEN1 (0.60) | KDM4ELMNAHSD17B10ALDH1A1GAA | |
| SCHEMBL6482423 | 0.69 | TSHR (0.59) | KDM4ELMNAHSD17B10ALDH1A1GAA | |
| SCHEMBL6480930 | 0.69 | ALDH1A1 (0.61) | KDM4ELMNAHSD17B10ALDH1A1GAA | |
| SCHEMBL11122413 | 0.65 | CA2 (0.62) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL9630225 | 0.65 | CA1 (0.65) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL11559995 | 0.64 | MAPT (0.53) | MAPTCA2CA1CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118684654-A | Compound with antihypertensive activity and synthesis method thereof | 复旦大学 | 2024-09-24 | — | — | CN | disclosed |