Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL8768511 | 0.93 | APEX1 (0.62) | APEX1ALDH1A1MAPTCASP6LMNA | |
| SCHEMBL8215970 | 0.85 | APEX1 (0.65) | APEX1ALDH1A1MAPTCASP6TSHR | |
| SCHEMBL9051152 | 0.85 | MAPT (0.84) | APEX1ALDH1A1MAPTTSHRCA2 | |
| SCHEMBL2001981 | 0.85 | APEX1 (0.72) | APEX1ALDH1A1MAPTCASP6TSHR | |
| SCHEMBL1996412 | 0.83 | APEX1 (0.70) | APEX1ALDH1A1MAPTCASP6TSHR | |
| SCHEMBL9049334 | 0.81 | MAPT (0.82) | APEX1ALDH1A1MAPTTSHRCA2 | |
| SCHEMBL28169588 | 0.80 | MAPT (0.80) | APEX1ALDH1A1MAPTTSHRCA2 | |
| SCHEMBL8768515 | 0.80 | APEX1 (0.52) | APEX1ALDH1A1MAPTCASP6LMNA | |
| SCHEMBL1025382 | 0.78 | APEX1 (0.69) | APEX1ALDH1A1MAPTCASP6TSHR | |
| SCHEMBL9050843 | 0.76 | MAPT (1.00) | APEX1ALDH1A1MAPTTSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |