Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422374 | 0.93 | APEX1 (0.71) | APEX1ALDH1A1MAPTCASP6LMNA | |
| SCHEMBL8768515 | 0.87 | APEX1 (0.52) | APEX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1996412 | 0.80 | APEX1 (0.70) | APEX1ALDH1A1MAPTMEN1KMT2A | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL6101 | 0.79 | VCAM1 (0.77) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL30234086 | 0.79 | VCAM1 (0.77) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8215970 | 0.79 | APEX1 (0.65) | APEX1ALDH1A1MAPTCASP6LMNA | |
| SCHEMBL9051152 | 0.79 | MAPT (0.84) | APEX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2001981 | 0.79 | APEX1 (0.72) | APEX1ALDH1A1MAPTCASP6LMNA | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL8028245 | 0.78 | VCAM1 (0.74) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL28165768 | 0.78 | VCAM1 (0.74) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791576-A2 | Leukotriene antagonistic benzoic acid derivatives | BAYER AG (DE) | 1997-08-27 | — | — | EP | disclosed |