Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | HCAR3 | P49019 | 11/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422374 | 0.85 | APEX1 (0.71) | APEX1HCAR3CASP6TSHRMAPT | |
| SCHEMBL2001981 | 0.83 | APEX1 (0.72) | APEX1HCAR3CASP6TSHRMAPT | |
| SCHEMBL1996412 | 0.82 | APEX1 (0.70) | APEX1HCAR3CASP6TSHRMAPT | |
| SCHEMBL9665036 | 0.80 | MAPT (0.60) | MAPTALDH1A1GAALMNA | |
| SCHEMBL3290188 | 0.80 | MAPT (0.60) | MAPTALDH1A1GAALMNA | |
| SCHEMBL11571002 | 0.80 | MAPT (0.60) | MAPTALDH1A1GAALMNA | |
| 4-Chloro-3-Nitrobenzoic Acid SCHEMBL8768511 | 0.79 | APEX1 (0.62) | APEX1CASP6MAPTALDH1A1LMNA | |
| SCHEMBL8217391 | 0.78 | KDM4E (0.50) | TSHRMAPTALDH1A1GAAPLA2G4B | |
| SCHEMBL8215974 | 0.78 | HCAR3 (0.64) | HCAR3CASP6TSHRMAPTGAA | |
| SCHEMBL3866808 | 0.77 | APEX1 (0.66) | APEX1HCAR3CASP6TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000056707-A1 | DIARYL THIOETHERS, COMPOSITIONS AND USES THEREOF | SEPRACOR, INC. (US) | 2000-09-28 | — | — | WO | disclosed |