Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422415 | 0.87 | HPGD (0.48) | HPGDMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8768516 | 0.82 | FFAR1 (0.52) | PPARDHPGDMEN1KMT2A | |
| SCHEMBL8422575 | 0.78 | SMN1; SMN2 (0.50) | HPGDMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8768533 | 0.76 | ALDH1A1 (0.51) | HPGDMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8422412 | 0.76 | MEN1 (0.48) | HPGDMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8420658 | 0.73 | SMN1; SMN2 (0.52) | HPGDMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8768505 | 0.73 | FFAR1 (0.44) | PPARDMEN1KMT2ALMNAPOLB | |
| SCHEMBL8420285 | 0.72 | SMN1; SMN2 (0.62) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL9798378 | 0.71 | PPARD (0.59) | PPARDHPGDMEN1MAPTKMT2A | |
| SCHEMBL17413764 | 0.70 | FFAR1 (0.57) | PPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |