Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420658 | 0.95 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTHPGDNPC1RAB9A | |
| SCHEMBL8419001 | 0.89 | KDM4E (0.57) | SMN1; SMN2HTTHPGDALDH1A1KDM4E | |
| SCHEMBL8418953 | 0.84 | ALDH1A1 (0.60) | SMN1; SMN2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL8422577 | 0.84 | HTT (0.54) | SMN1; SMN2HTTKDM4EPOLBGAA | |
| SCHEMBL8420285 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL8420661 | 0.83 | HTT (0.55) | SMN1; SMN2HTTHPGDRAB9APLK1 | |
| SCHEMBL8768524 | 0.79 | ALDH1A1 (0.59) | SMN1; SMN2HTTALDH1A1KDM4EPLK1 | |
| SCHEMBL8422404 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL8422409 | 0.78 | PPARD (0.53) | HPGDNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8767987 | 0.76 | HTT (0.49) | SMN1; SMN2HTTHPGDPOLBLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872280-A | RESPIRATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-16 | — | — | US | disclosed |