⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332771 | 0.77 | — | — | |
| SCHEMBL767783 | 0.76 | — | — | |
| SCHEMBL844948 | 0.74 | — | — | |
| SCHEMBL845080 | 0.72 | — | — | |
| SCHEMBL8847857 | 0.70 | — | — | |
| SCHEMBL844429 | 0.70 | — | — | |
| SCHEMBL8751731 | 0.69 | — | — | |
| SCHEMBL1817190 | 0.69 | SLC7A5 (0.38) | — | |
| SCHEMBL1817909 | 0.69 | — | — | |
| SCHEMBL14351292 | 0.69 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949238-A1 | SUBSTITUTED PROPIONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |
| EP-0015240-A1 | Azacyclyl (thio) ureidoacetyl compounds and their preparation | CIBA-GEIGY AG (CH) | 1980-09-03 | — | — | EP | disclosed |