SCHEMBL767783

SCHEMBL767783

NC(=O)OCOC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4997379 0.85
SCHEMBL13577883 0.85 ALOX15 (0.43)
SCHEMBL7372172 0.83 ALOX15 (0.55)
SCHEMBL2482637 0.81
SCHEMBL15998188 0.81
SCHEMBL9868713 0.81
SCHEMBL13577882 0.81 CYP1A2 (0.41)
SCHEMBL6066229 0.81 ALOX15 (0.46)
SCHEMBL13577871 0.79 LMNA (0.43)
SCHEMBL13577869 0.79 CHRNB2 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118541136-A Skin microbiome friendly sunscreens 巴斯夫欧洲公司 2024-08-23 CN claimed
US-20240226320-A1 DRUG CONJUGATES WITH SELF-STABILIZING LINKERS HAVING IMPROVED PHYSIOCHEMICAL PROPERTIES SEAGEN INC (US) 2024-07-11 US claimed
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-06-27 US claimed
US-20240207435-A1 PROCESS FOR THE PREPARATION OF GLUCURONIDE DRUG-LINKERS AND INTERMEDIATES THEREOF SEAGEN INC (US) 2024-06-27 US claimed
WO-2024074813-A1 A COMPOUND AND ITS USE FOR DETECTING A DISEASE IN THE EXHALED BREATH OF A SUBJECT OWLSTONE MEDICAL LIMITED (GB) 2024-04-11 WO claimed
EP-4308171-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS Seagen Inc. (US) 2024-01-24 EP claimed
EP-4212181-A2 METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES Seagen Inc. (US) 2023-07-19 EP claimed
CN-114470824-A Device and method for preparing hexamethylene diisocyanate by pyrolyzing intermediate of hexamethylene dicarbamate 中国石油化工股份有限公司 2022-05-13 CN claimed
US-20220054650-A1 Methylene Carbamate Linkers for use with Targeted-Drug Conjugates SEATTLE GENETICS, INC. 2022-02-24 US claimed
US-11116847-B2 Methylene carbamate linkers for use with targeted-drug conjugates SEAGEN INC. (US) 2021-09-14 US claimed
US-20160303254-A1 METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES SEAGEN INC. 2016-10-20 US claimed
CN-105813653-A Methylene carbamate linkers for use with target-drug conjugates 西雅图基因公司 2016-07-27 CN claimed
CN-105536056-A Preparation method of tissue engineered artificial swallowing valve NINGBO MEDICAL TREAT CENTER LIHUILI HOSPITAL 2016-05-04 CN claimed
WO-2015095755-A1 METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES SEATTLE GENETICS, INC. (US) 2015-06-25 WO claimed
US-20140187527-A1 Macrocyclic Compounds And Metal Complexes For Bioimaging And Biomedical Applications NATIONAL YANG MING UNIVERSITY (TW) 2014-07-03 US claimed
US-20140179875-A1 SULFURIZATION REAGENTS ON SOLID SUPPORTS GIRINDUS AMERICA, INC. (US) 2014-06-26 US claimed
WO-2013017469-A1 SULFURIZATION REAGENTS ON SOLID SUPPORTS GIRINDUS AMERICA, INC. (US) 2013-02-07 WO claimed
US-20120071640-A1 Sulfurizing reagents and their use for oligonucleotides synthesis GIRINDUS AMERICA, INC. (US) 2012-03-22 US claimed
EP-2382227-A1 SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS Girindus America, Inc. (US) 2011-11-02 EP claimed
WO-2010072831-A1 SULFURIZING REAGENTS AND THEIR USE FOR OLIGONUCLEOTIDES SYNTHESIS GIRINDUS AMERICA, INC (US) 2010-07-01 WO claimed