⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254461 | 0.77 | — | — | |
| SCHEMBL845080 | 0.77 | — | — | |
| SCHEMBL6140626 | 0.77 | — | — | |
| SCHEMBL322669 | 0.76 | — | — | |
| SCHEMBL844429 | 0.75 | — | — | |
| SCHEMBL8847857 | 0.75 | — | — | |
| SCHEMBL8422790 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL28155621 | 0.74 | ALDH1A1 (0.56) | — | |
| SCHEMBL14351292 | 0.73 | TP53 (0.32) | — | |
| SCHEMBL1823492 | 0.73 | ALDH1A1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 649 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016204991-A1 | IBRUTINIB PRODRUGS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-12-22 | — | — | WO | claimed |
| US-9394312-B1 | Ibrutinib prodrugs, pharmaceutical compositions thereof, and methods of use | Nguyen, Mark Quang (US) | 2016-07-19 | — | — | US | claimed |
| WO-2014022752-A1 | MACROCYCLES AS PIM INHIBITORS | AMGEN INC. (US) | 2014-02-06 | — | — | WO | claimed |
| US-20080261314-A1 | FLUORESCENT PROBE FOR ZINC | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2008-10-23 | — | — | US | claimed |
| WO-2007054965-A2 | PROCESS FOR PREPARATION OF TETRAZOLES FROM AROMATIC CYANO DERIVATIVES | ALEMBIC LIMITED (IN) | 2007-05-18 | — | — | WO | claimed |
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | claimed |
| US-20040235902-A1 | Fluorescent probes for zinc | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2004-11-25 | — | — | US | claimed |
| EP-1007037-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-10-06 | — | — | EP | claimed |
| EP-1403268-A1 | FLUORESCENT PROBES FOR ZINC | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2004-03-31 | — | — | EP | claimed |
| US-6677369-B2 | CARBOXIMIDAMIDE DERIVATIVE ANTICOAGULANTS INHIBIT FACTOR XA | ELI LILLY AND COMPANY | 2004-01-13 | — | — | US | claimed |
| EP-0603712-A2 | Heterocyclic compounds having angiotensin II antagonistic activity and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-06-29 | — | — | EP | claimed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | claimed |
| US-4945171-A | FLUORESCENT DYES | MOLECULAR PROBES, INC. (US) | 1990-07-31 | — | — | US | claimed |
| EP-0150458-B1 | CEPHEM COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1989-11-23 | — | — | EP | claimed |
| US-4705784-A | ORAL DRUGS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-10 | — | — | US | claimed |
| EP-0150458-A2 | Cephem compounds | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1985-08-07 | — | — | EP | claimed |
| US-4323567-A | BACTERICIDES | NARISADA MASAYUKI | 1982-04-06 | — | — | US | claimed |
| EP-0041047-A2 | Dioxide compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-12-02 | — | — | EP | claimed |
| US-4180571-A | Arylmalonamido-1-oxadethiacephalosporins | SHIONOGI & CO., LTD. (JP) | 1979-12-25 | — | — | US | claimed |
| US-4138486-A | BACTERICIDES | SHIONOGI & CO., LTD. (JP) | 1979-02-06 | — | — | US | claimed |