Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.53 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487954 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL17205245 | 0.78 | PTGS2 (0.59) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL4940447 | 0.78 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7104819 | 0.77 | PTGS2 (0.49) | PTGS2PTGS1LOX | |
| SCHEMBL28111372 | 0.77 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL4941143 | 0.75 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL6050679 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL6050840 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL15650181 | 0.74 | PTGS2 (0.58) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL18876343 | 0.74 | PTGS2 (0.76) | PTGS2PTGS1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |