Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160376 | 0.83 | PTGS2 (0.54) | PTGS2PTGS1NR1H2NR1H3S1PR1 | |
| SCHEMBL14832293 | 0.77 | CYP11B1 (0.56) | CFTRPDE3BPDE3AS1PR1ERN1 | |
| SCHEMBL8423019 | 0.77 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL4940447 | 0.77 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL17205245 | 0.77 | PTGS2 (0.59) | PTGS2PTGS1ERN1 | |
| SCHEMBL1927394 | 0.76 | GLA (0.58) | CFTRPDE3BPDE3AS1PR1TSHR | |
| SCHEMBL28219626 | 0.75 | TSHR (0.46) | PTGS2PTGS1NR1H2NR1H3TSHR | |
| SCHEMBL16446879 | 0.75 | CYP11B2 (0.60) | CFTRPDE3BPDE3AS1PR1 | |
| SCHEMBL28110779 | 0.75 | PIK3CA (0.46) | PTGS2PTGS1NR1H2NR1H3 | |
| SCHEMBL4011934 | 0.74 | NR1H2 (0.83) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188040-B | A kind of Fevipiprant and its intermediate preparation method | 浙江宏鑫染化材料有限公司 | 2018-03-23 | — | — | CN | claimed |
| CN-106188040-A | A kind of Fevipiprant and the preparation method of intermediate thereof | 浙江宏鑫染化材料有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-108484595-A | A kind of succinct synthetic method of asthmatic medicament Fevipiprant | 天津科技大学 | 2018-09-04 | — | — | CN | disclosed |
| CN-106188040-B | A kind of Fevipiprant and its intermediate preparation method | 浙江宏鑫染化材料有限公司 | 2018-03-23 | — | — | CN | disclosed |