Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | GRK5 | P34947 | 1/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | PRKX | P51817 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196805 | 0.89 | ALDH1A1 (0.38) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL8424942 | 0.87 | ALDH1A1 (0.36) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL8421784 | 0.86 | ALDH1A1 (0.39) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL8421766 | 0.86 | HRH2 (0.36) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL8424929 | 0.81 | ALDH1A1 (0.39) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL8421115 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL196648 | 0.78 | ALDH1A1 (0.37) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL13206640 | 0.78 | ALDH1A1 (0.38) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL197925 | 0.77 | ALDH1A1 (0.45) | ALDH1A1ESR1CYP3A4ESR2NR1H4 | |
| SCHEMBL196285 | 0.75 | ELANE (0.54) | ALDH1A1ESR1CYP3A4ESR2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856561-A | Bisphenol carboxylic acid tertiary ester derivatives and chemically amplified positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | claimed |
| US-5856561-A | Bisphenol carboxylic acid tertiary ester derivatives and chemically amplified positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |