Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421259 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL8421240 | 0.84 | KDM4E (0.47) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8423281 | 0.83 | KDM4E (0.48) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8419850 | 0.83 | ACLY (0.57) | KDM4EACLYPIK3CGPIK3CATUBB4A | |
| SCHEMBL8423384 | 0.83 | STAT3 (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8423244 | 0.83 | KDM4E (0.46) | KDM4EPIK3CDMEN1KMT2AACLY | |
| SCHEMBL8419328 | 0.82 | KDM4E (0.53) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8423385 | 0.82 | KDM4E (0.47) | KDM4EACLYPIK3CGTUBB4ATUBB | |
| SCHEMBL8421277 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4EGAAHPGDMEN1 | |
| SCHEMBL8423073 | 0.82 | STAT3 (0.48) | MAPTALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |