Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842734 | 0.86 | CYP1A2 (0.34) | TAAR1ALDH1A1CYP1A2 | |
| SCHEMBL14524351 | 0.72 | TDP1 (0.36) | TDP1SIGMAR1TAAR1ATMALDH1A1 | |
| SCHEMBL19926794 | 0.69 | KCNH2 (0.46) | TDP1TAAR1ATMALDH1A1HPGD | |
| SCHEMBL8058367 | 0.68 | ESR1 (0.31) | — | |
| SCHEMBL3627315 | 0.66 | — | — | |
| SCHEMBL8385789 | 0.66 | TDP1 (0.48) | TDP1TAAR1ATMALDH1A1HPGD | |
| SCHEMBL8385776 | 0.65 | TDP1 (0.48) | TDP1TAAR1ATMALDH1A1HPGD | |
| SCHEMBL6420860 | 0.65 | TDP1 (0.52) | TDP1TAAR1ATMALDH1A1HPGD | |
| SCHEMBL3389806 | 0.65 | TDP1 (0.52) | TDP1TAAR1L3MBTL1ATMALDH1A1 | |
| SCHEMBL16550634 | 0.65 | TDP1 (0.52) | TDP1TAAR1L3MBTL1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143363-B2 | Polymerizable composition | HENKEL AG & CO. KGAA (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20110105680-A1 | Polymerizable Composition | HENKEL AG & CO. KGAA (DE) | 2011-05-05 | — | — | US | disclosed |