SCHEMBL8423545

SCHEMBL8423545

Oc1c(C=Cc2ccccc2)ccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 4/20 0.55
ABCG2 Q9UNQ0 2/20 0.55
TRPA1 O75762 1/20 0.50
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
PTPN22 Q9Y2R2 1/20 0.48
KDM4E B2RXH2 2/20 0.47
LDHA P00338 1/20 0.46
RELA Q04206 1/20 0.46
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
CHAT P28329 1/20 0.44
CYP1A1 P04798 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8423542 1.00 CYP1B1 (0.55) CYP1B1ABCG2TRPA1PTGS1PTGS2
SCHEMBL7036224 0.89 KMT2A (0.54) CYP1B1ABCG2PTGS1PTGS2PTPN22
(Z)-1,2-Diphenylethene SCHEMBL29177829 0.80 ALDH1A1 (0.63) CYP1B1ABCG2KDM4ERELANPC1
SCHEMBL8537074 0.79 PTPN22 (0.50) CYP1B1ABCG2PTGS1PTGS2PTPN22
SCHEMBL992363 0.79 RELA (0.47) CYP1B1ABCG2TRPA1KDM4ERELA
SCHEMBL992362 0.79 RELA (0.47) CYP1B1ABCG2TRPA1KDM4ERELA
SCHEMBL8537080 0.79 PTPN22 (0.50) CYP1B1ABCG2PTGS1PTGS2PTPN22
SCHEMBL765996 0.79 CYP1B1 (0.54) CYP1B1ABCG2PTPN22KDM4ELDHA
SCHEMBL765995 0.79 CYP1B1 (0.54) CYP1B1ABCG2PTPN22KDM4ELDHA
SCHEMBL10774372 0.78 RELA (0.46) CYP1B1ABCG2TRPA1KDM4ERELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1168812-C Detergent composition 普罗格特-甘布尔公司 2004-09-29 CN disclosed
EP-0639047-B1 HERBICIDAL COMPOSITIONS KVK AGRO AS (DK) 1999-10-06 EP disclosed
CN-1225675-A Detergent composition PROCTER & GAMBLE (US) 1999-08-11 CN disclosed
EP-0637910-B1 STABILIZED HERBICIDE COMPOSITIONS KVK AGRO AS (DK) 1996-06-05 EP disclosed
EP-0639047-A1 HERBICIDAL COMPOSITIONS KVK AGRO A/S (DK) 1995-02-22 EP disclosed
EP-0637910-A1 STABILIZED HERBICIDE COMPOSITIONS. KVK AGRO AS (DK) 1995-02-15 EP disclosed
WO-1992009195-A1 HERBICIDAL COMPOSITIONS KVK AGRO A/S (DK) 1992-06-11 WO disclosed
WO-1992009197-A1 STABILIZED HERBICIDE COMPOSITIONS KVK AGRO A/S (DK) 1992-06-11 WO disclosed