Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427138 | 0.90 | CA2 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL9189351 | 0.89 | MAPT (0.39) | GRIK1SLC1A2SLC1A1GRIK2 | |
| SCHEMBL4957663 | 0.88 | DPP4 (0.34) | — | |
| SCHEMBL7058113 | 0.87 | AKR1C3 (0.32) | — | |
| SCHEMBL3685443 | 0.86 | — | — | |
| SCHEMBL8083662 | 0.79 | — | — | |
| SCHEMBL8083660 | 0.79 | — | — | |
| SCHEMBL158890 | 0.77 | AKR1C3 (0.31) | — | |
| SCHEMBL164963 | 0.74 | — | — | |
| SCHEMBL3659175 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947857-A2 | Process for providing an optical element and optical element obtainable by such a process | Akzo Nobel N.V. (NL) | 1999-10-06 | — | — | EP | claimed |
| EP-0947857-A2 | Process for providing an optical element and optical element obtainable by such a process | Akzo Nobel N.V. (NL) | 1999-10-06 | — | — | EP | disclosed |