Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8421920 | 0.93 | PTGES (0.44) | NPSR1RXFP1KDM4EMEN1MAPT | |
| SCHEMBL8688483 | 0.84 | PTGS1 (0.51) | NPSR1RXFP1KDM4ECA1CA2 | |
| SCHEMBL8688502 | 0.81 | NPSR1 (0.35) | NPSR1RXFP1KDM4ECA1CA2 | |
| SCHEMBL8693627 | 0.81 | PTGS1 (0.38) | NPSR1RXFP1KDM4ECA1CA2 | |
| SCHEMBL8689135 | 0.81 | PTGS1 (0.43) | NPSR1RXFP1KDM4ECA1CA2 | |
| SCHEMBL8693716 | 0.81 | PTGS1 (0.43) | NPSR1RXFP1KDM4ECA1CA2 | |
| SCHEMBL8424177 | 0.80 | PTGES (0.43) | NPSR1MEN1MAPTKMT2APTGES | |
| SCHEMBL8424009 | 0.80 | PTGES (0.43) | NPSR1RXFP1KDM4EMEN1MAPT | |
| SCHEMBL8423988 | 0.80 | PTGES (0.43) | NPSR1MEN1MAPTKMT2APTGES | |
| SCHEMBL8423891 | 0.80 | ALDH1A1 (0.43) | NPSR1MEN1MAPTKMT2APTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |