SCHEMBL8423656

SCHEMBL8423656

Nc1cc(C(=O)c2ccc(S(=O)(=O)CCO)c(N)c2)ccc1S(=O)(=O)CCO

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.62
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GAA P10253 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 2/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38
CDC25B P30305 1/20 0.38
KYNU Q16719 2/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8552518 0.81 CA2 (0.42) CA2NPC1USP2RAB9ASMN1; SMN2
SCHEMBL5474330 0.81 CA2 (0.68) CA2HSD17B10GAAALDH1A1L3MBTL1
SCHEMBL10606415 0.79 CA2 (0.81) CA2RAB9AHSD17B10GAAALDH1A1
SCHEMBL8285549 0.78 CA2 (0.64) CA2SMN1; SMN2HSD17B10ALDH1A1
SCHEMBL8423628 0.74 KMT2A (0.46) CA2ALDH1A1MAPK1MAPTHTT
SCHEMBL635315 0.73 CA2 (0.57) CA2GAAKYNU
SCHEMBL10605653 0.72 CA2 (0.56) CA2HSD17B10GAAALDH1A1MAPT
SCHEMBL8441914 0.71 CDC25B (0.54) CA2NPC1RAB9ASMN1; SMN2HSD17B10
SCHEMBL9877386 0.70 CA2 (0.54) CA2USP2HSD17B10GAAALDH1A1
Sulfuric Acid SCHEMBL27866658 0.70 CA2 (0.54) CA2GAAKYNU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0731089-B1 Aniline derivatives BASF AG (DE) 1999-10-20 EP disclosed
US-5625089-A CHEMICAL INTERMEDIATES FOR REACTIVE DYES BASF AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed
EP-0731089-A1 Aniline derivatives BASF AKTIENGESELLSCHAFT (DE) 1996-09-11 EP disclosed