Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811326 | 0.83 | CA2 (0.47) | KMT2AALDH1A1MEN1MAPK1MAPT | |
| SCHEMBL6932164 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1MAPK1KDM4ECA2POLB | |
| SCHEMBL8423656 | 0.74 | CA2 (0.62) | ALDH1A1MAPK1MAPTKDM4ECA2 | |
| SCHEMBL1368798 | 0.72 | PTGDR2 (0.45) | KMT2AALDH1A1MEN1MAPK1MAPT | |
| SCHEMBL8913198 | 0.72 | CA2 (0.40) | KMT2AALDH1A1MEN1MAPTCA2 | |
| SCHEMBL9148008 | 0.70 | ALDH1A1 (0.48) | KMT2AALDH1A1MEN1 | |
| SCHEMBL9150222 | 0.69 | ALDH1A1 (0.43) | KMT2AALDH1A1MEN1POLB | |
| SCHEMBL11783919 | 0.67 | GAA (0.56) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL5711952 | 0.67 | ALDH1A1 (0.73) | KMT2AALDH1A1MAPTKDM4ECA2 | |
| SCHEMBL2890963 | 0.67 | KDM4E (0.65) | KMT2AALDH1A1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731089-B1 | Aniline derivatives | BASF AG (DE) | 1999-10-20 | — | — | EP | disclosed |
| US-5625089-A | CHEMICAL INTERMEDIATES FOR REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| EP-0731089-A1 | Aniline derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1996-09-11 | — | — | EP | disclosed |