Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | DDX3X | O00571 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423682 | 1.00 | MEN1 (0.34) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL6946010 | 0.96 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL6946007 | 0.96 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8425576 | 0.91 | KAT8 (0.41) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8425574 | 0.91 | KAT8 (0.41) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL6946132 | 0.86 | KAT8 (0.44) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL6946129 | 0.86 | KAT8 (0.44) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8423685 | 0.84 | MEN1 (0.35) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8425734 | 0.82 | KMT2A (0.38) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL8425736 | 0.82 | KMT2A (0.38) | MEN1ALDH1A1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |