Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425576 | 1.00 | KAT8 (0.41) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6946132 | 0.95 | KAT8 (0.44) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6946129 | 0.95 | KAT8 (0.44) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8423684 | 0.91 | MEN1 (0.34) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8423682 | 0.91 | MEN1 (0.34) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8428136 | 0.87 | KMT2A (0.40) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8428139 | 0.87 | KMT2A (0.40) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8428127 | 0.86 | ALDH1A1 (0.49) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8428125 | 0.86 | ALDH1A1 (0.49) | KAT8ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8425734 | 0.86 | KMT2A (0.38) | KAT8ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |