Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.41 |
| ▸ | CTSS | P25774 | 11/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423620 | 0.78 | CTSK (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5215045 | 0.76 | CTSS (0.43) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL31173277 | 0.74 | CTSS (0.42) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL3646397 | 0.74 | CTSS (0.42) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL13975709 | 0.73 | KDM4A (0.41) | CTSKATMGAACA12CA1 | |
| SCHEMBL30466775 | 0.72 | KDM4A (0.40) | CTSKATMGAACA12CA1 | |
| SCHEMBL11573047 | 0.69 | CTSS (0.48) | CTSKCTSSATMGAACA1 | |
| SCHEMBL8422170 | 0.69 | CTSS (0.45) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL8422169 | 0.69 | CTSS (0.45) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL3220161 | 0.68 | CTSK (0.48) | CTSKCTSSATMCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874472-A | Aminoacid derivatives as no synthase inhibitors | GLAXO WELLCOME INC. (US) | 1999-02-23 | — | — | US | disclosed |