Indene

Indene

SCHEMBL8423912

C1=Cc2ccccc2C1.O=S(=O)(O)c1cc2ccccc2o1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.48
AKR1B1 P15121 2/20 0.39
CD74 P04233 1/20 0.37
MIF P14174 1/20 0.37
FLT3 P36888 1/20 0.36
HPGD P15428 2/20 0.36
TYR P14679 1/20 0.36
DAO P14920 1/20 0.36
CA1 P00915 4/20 0.35
CA9 Q16790 3/20 0.35
CA12 O43570 2/20 0.35
CCR2 P41597 5/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
HRH4 Q9H3N8 1/20 0.34
TSHR P16473 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31695410 0.82 CA2 (0.67) CA2AKR1B1FLT3HPGDTYR
SCHEMBL1655317 0.82 CA2 (0.67) CA2AKR1B1FLT3HPGDTYR
Hydrochloric Acid SCHEMBL27720604 0.81 CA2 (0.65) CA2AKR1B1FLT3HPGDTYR
Indene SCHEMBL27714403 0.77 CA1 (0.46) CA2HPGDCA1KDM4ETSHR
Indene SCHEMBL19837524 0.76 CA1 (0.37) CA2AKR1B1FLT3HPGDTYR
Coumarin SCHEMBL7633181 0.73 CA12 (0.62) CA2AKR1B1HPGDCA1CA9
Indene SCHEMBL27535407 0.72 CA1 (0.42) CA2CA1CA9TSHRMEN1
Anthracene SCHEMBL28057537 0.72 CA1 (0.47) CA2HPGDCA1ALDH1A1MAPT
Naphthalene SCHEMBL2783692 0.72 CA1 (0.50) CA2CA1TSHR
Indene SCHEMBL8336138 0.70 CA1 (0.55) CA2CA1TSHRMAOBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671458-B1 Process for moving highly viscous petroleum products ENI SPA (IT) 1999-10-20 EP claimed