Coumarin

Coumarin

SCHEMBL7633181

C1=Cc2ccccc2C1.O=c1ccc2ccccc2o1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.62
CA9 Q16790 8/20 0.62
CA1 P00915 7/20 0.62
CA4 P22748 5/20 0.62
CA7 P43166 5/20 0.62
CA14 Q9ULX7 5/20 0.62
CA2 P00918 4/20 0.62
CA5A P35218 4/20 0.62
CA3 P07451 4/20 0.62
CA6 P23280 4/20 0.62
CA5B Q9Y2D0 3/20 0.62
MCL1 Q07820 3/20 0.62
TDP1 Q9NUW8 3/20 0.62
LMNA P02545 2/20 0.62
SOST Q9BQB4 1/20 0.62
PGR P06401 2/20 0.41
HPGD P15428 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL7526019 0.88 CA12 (0.49) CA12CA9CA1CA4CA7
Coumarin SCHEMBL1038138 0.79 CA12 (1.00) CA12CA9CA1CA4CA7
Coumarin SCHEMBL29385611 0.79 CA12 (1.00) CA12CA9CA1CA4CA7
Coumarin SCHEMBL28886137 0.79 CA12 (1.00) CA12CA9CA1CA4CA7
Coumarin SCHEMBL3441294 0.79 CA12 (1.00) CA12CA9CA1CA4CA7
Coumarin SCHEMBL6252 0.79 CA12 (1.00) CA12CA9CA1CA4CA7
Coumarin SCHEMBL621751 0.79 CA12 (1.00) CA12CA9CA1CA4CA7
Coumarin SCHEMBL8144767 0.77 CA12 (0.95) CA12CA9CA1CA4CA7
Coumarin SCHEMBL531571 0.77 CA12 (0.95) CA12CA9CA1CA4CA7
Coumarin SCHEMBL4958503 0.77 CA12 (0.95) CA12CA9CA1CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5094918-A Safety glass BRIDGESTONE CORPORATION (JP) 1992-03-10 US claimed
US-4230785-A Pressure sensitive adhesive elecrophotographic reproduction sheets DENNISON MANUFACTURING COMPANY (US) 1980-10-28 US claimed
CN-118259568-A Toner bag 佳能株式会社 2024-06-28 CN disclosed
CN-117850181-A Toner and method for producing the same 佳能株式会社 2024-04-09 CN disclosed
CN-117545802-A Thermoplastic elastomer composition, molded body thereof and use thereof 三井化学株式会社 2024-02-09 CN disclosed
CN-115244151-B Adhesive tape 株式会社寺冈制作所 2023-12-12 CN disclosed
CN-115916553-A Tyre for vehicle wheels 住友橡胶工业株式会社 2023-04-04 CN disclosed
CN-115697725-A Tyre for vehicle wheels 住友橡胶工业株式会社 2023-02-03 CN disclosed
CN-110178248-B Protective film, battery, and method for manufacturing battery 大日本印刷株式会社 2022-08-19 CN disclosed
CN-111344349-A Resin composition, material for melt molding, multilayer structure, and material for liquid packaging 三菱化学株式会社 2020-06-26 CN disclosed
CN-110178248-A Protective film, battery, and method for manufacturing battery 大日本印刷株式会社 2019-08-27 CN disclosed
CN-1942313-B Surface protective sheet NICHIBAN KK 2011-10-26 CN disclosed
CN-1942313-A Surface protective sheet NICHIBAN KK (JP) 2007-04-04 CN disclosed
US-6469089-B2 MIXING WITH REINFORCING FILLER MIXTURES CABOT CORPORATION 2002-10-22 US disclosed
US-20020132901-A1 ELASTOMERIC COMPOUNDS WITH IMPROVED WET SKID RESISTANCE AND METHODS TO IMPROVE WET SKID RESISTANCE CABOT CORPORATION 2002-09-19 US disclosed
EP-1237999-A1 ELASTOMERIC COMPOUNDS WITH IMPROVED WET SKID RESISTANCE AND METHODS TO IMPROVE WET SKID RESISTANCE CABOT CORPORATION (US) 2002-09-11 EP disclosed
WO-2001027192-A1 ELASTOMERIC COMPOUNDS WITH IMPROVED WET SKID RESISTANCE AND METHODS TO IMPROVE WET SKID RESISTANCE CABOT CORPORATION (US) 2001-04-19 WO disclosed