Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 10/20 | 0.67 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3886681 | 0.82 | CD274 (1.00) | CD274PDCD1ALDH1A1GAAMAPT | |
| SCHEMBL8425478 | 0.78 | CD274 (0.48) | CD274PDCD1ALDH1A1ATMGAA | |
| SCHEMBL8425824 | 0.78 | KMT2A (0.49) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8427533 | 0.77 | MAPT (0.65) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8425552 | 0.76 | POLB (0.55) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8428070 | 0.74 | CA1 (0.54) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8425596 | 0.74 | GAA (0.47) | CD274PDCD1ALDH1A1GAAMAPT | |
| SCHEMBL8428126 | 0.72 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8423248 | 0.72 | APP (0.43) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL28847231 | 0.70 | GAA (0.48) | ALDH1A1ATMGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |