Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428070 | 0.88 | CA1 (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6953270 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8423248 | 0.85 | APP (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8427533 | 0.83 | MAPT (0.65) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8428161 | 0.82 | CYP2C9 (0.51) | ALDH1A1LMNATSHRPOLB | |
| SCHEMBL8425552 | 0.82 | POLB (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8428115 | 0.82 | MAPK1 (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9023579 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8425824 | 0.74 | KMT2A (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8425596 | 0.73 | GAA (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |