Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420855 | 0.93 | KDM1A (0.40) | ALOX5APFEN1MALT1KDM1APTGES2 | |
| SCHEMBL8422278 | 0.93 | MALT1 (0.38) | MALT1KDM1AALDH1A1CYP3A4MAPT | |
| SCHEMBL8424102 | 0.88 | KDM1A (0.40) | MALT1KDM1AMAPTSMN1; SMN2KIT | |
| SCHEMBL8422266 | 0.88 | KDM1A (0.43) | MALT1KDM1ACYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL8420731 | 0.88 | KDM1A (0.43) | MALT1KDM1ACYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL8421767 | 0.87 | MALT1 (0.39) | MALT1KDM1AALDH1A1CYP3A4MAPT | |
| SCHEMBL8420714 | 0.87 | TP53 (0.44) | KDM1A | |
| SCHEMBL8421839 | 0.87 | PTGS2 (0.42) | ALOX5APFEN1MALT1KDM1AALDH1A1 | |
| SCHEMBL8420734 | 0.85 | MALT1 (0.43) | MALT1KDM1ACYP3A4MAPTKAT6A | |
| SCHEMBL8420739 | 0.85 | MALT1 (0.40) | MALT1KDM1AMAPTKAT6ANAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908852-A | 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation | G. D. SEARLE & CO. (US) | 1999-06-01 | — | — | US | disclosed |