SCHEMBL8424404

SCHEMBL8424404

CC(=O)C(NCCN)C(C(C)=O)(C(C)=O)N(C(C)=O)C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28710177 0.77 GGT1 (0.33)
SCHEMBL5072477 0.65 GGT1 (0.38)
SCHEMBL8038154 0.64 GGT1 (0.37)
SCHEMBL26452831 0.64
SCHEMBL11306525 0.64 GGT1 (0.37)
SCHEMBL3749598 0.63 GGT1 (0.42)
SCHEMBL7489694 0.62 CYP2C9 (0.31)
SCHEMBL24503897 0.61 GGT1 (0.43)
Ethylenediamine SCHEMBL10970096 0.60 PAOX (0.30)
Acetic Acid SCHEMBL28069700 0.60 GGT1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700900-B1 PROCESS FOR PRODUCING ACYLOXYBENZENESULFONIC ACID OR SALT THEREOF KAO CORP (JP) 1999-11-03 EP disclosed
EP-0757983-B1 Process for the preparation of tertiary amine oxides CLARIANT GMBH (DE) 1999-10-13 EP disclosed
US-5710333-A ADDING AMINE OXIDE BEFORE REACTION TO INHIBIT GELATION AND FOAMING; OXIDATION OF TERTIARY AMINE HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
US-5606104-A SULFONATING THE CORRESPONDING ACYLOXYBENZENE KAO CORPORATION (JP) 1997-02-25 US disclosed
EP-0757983-A1 Process for the preparation of tertiary amine oxides HOECHST AKTIENGESELLSCHAFT (DE) 1997-02-12 EP disclosed
CN-1125939-A Process for producing acyloxybenzenesulfonic acid or salt thereof KAO CORP (JP) 1996-07-03 CN disclosed
EP-0700900-A1 PROCESS FOR PRODUCING ACYLOXYBENZENESULFONIC ACID OR SALT THEREOF Kao Corporation (JP) 1996-03-13 EP disclosed