Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.37 |
| ▸ | FEN1 | P39748 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423386 | 0.92 | PTGS1 (0.39) | PTGS1PTGS2SGK1ALOX5APFEN1 | |
| SCHEMBL8424482 | 0.87 | PTGS2 (0.47) | PTGS1PTGS2CA9MEN1KMT2A | |
| SCHEMBL8423053 | 0.81 | PTGS1 (0.42) | PTGS1PTGS2SGK1ALOX5APFEN1 | |
| SCHEMBL8421107 | 0.81 | PTGS2 (0.47) | PTGS1PTGS2SGK1ALOX5APFEN1 | |
| SCHEMBL8423389 | 0.79 | PTGS2 (0.46) | PTGS1PTGS2CA9MEN1KMT2A | |
| SCHEMBL8423196 | 0.78 | SGK1 (0.42) | PTGS1PTGS2SGK1ALOX5APFEN1 | |
| SCHEMBL8423260 | 0.78 | SGK1 (0.42) | PTGS1PTGS2SGK1ALOX5APFEN1 | |
| SCHEMBL8419905 | 0.73 | PTGS2 (0.40) | PTGS1PTGS2SGK1ALOX5APFEN1 | |
| SCHEMBL8776868 | 0.72 | PTGS2 (0.57) | PTGS1PTGS2CA9MEN1KMT2A | |
| SCHEMBL8421300 | 0.71 | PTGS2 (0.39) | PTGS1PTGS2SGK1F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916905-A | ANTIARTHRITIC AGENTS; ANALGESICS; ANTIPYRETICS | G. D. SEARLE & CO. (US) | 1999-06-29 | — | — | US | disclosed |