SCHEMBL8424495

SCHEMBL8424495

[CH2]/C(=C\c1ccccc1O)c1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
GUSB P08236 1/20 0.47
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 6/20 0.42
HPGD P15428 5/20 0.42
CYP3A4 P08684 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRPA1 O75762 1/20 0.41
CA2 P00918 4/20 0.40
CA12 O43570 3/20 0.40
ALDH1A1 P00352 3/20 0.40
CA9 Q16790 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8424497 1.00 BCHE (0.47) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL7026918 0.75 RAB9A (0.51) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL9261761 0.75 RAB9A (0.51) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL4415876 0.73 BCHE (0.46) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL4415872 0.73 BCHE (0.46) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL9114625 0.72 RAB9A (0.45) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL7574403 0.72 BCHE (0.41) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL8982379 0.69 TRIM24 (0.52) TRIM24TRIM33RAB9AKDM4EHPGD
SCHEMBL2037793 0.69 TRIM24 (0.52) TRIM24TRIM33RAB9AKDM4EHPGD
SCHEMBL10857084 0.69 TRIM24 (0.52) BCHEGUSBTRIM24TRIM33RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5874645-A HEATING DIHYDROXYDIPHENYL COMPOUND WITH ACID TO CAUSE FORMATION OF DOUBLE BOND THE DOW CHEMICAL COMPANY (US) 1999-02-23 US disclosed