SCHEMBL7574403

SCHEMBL7574403

C=CC/C(=C\c1ccccc1O)c1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.41
GUSB P08236 1/20 0.41
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
RAB9A P51151 1/20 0.38
CA12 O43570 7/20 0.38
CA2 P00918 7/20 0.38
KDM4E B2RXH2 4/20 0.38
SIRT2 Q8IXJ6 1/20 0.38
HPGD P15428 3/20 0.37
CYP3A4 P08684 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA9 Q16790 7/20 0.36
CA1 P00915 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22411162 0.83 MAPT (0.41) BCHERAB9ACA12CA2KDM4E
SCHEMBL4453043 0.80 ACHE (0.41) BCHEGUSBCA12CA2KDM4E
SCHEMBL9114625 0.80 RAB9A (0.45) BCHEGUSBTRIM24TRIM33RAB9A
SCHEMBL4453039 0.80 ACHE (0.41) BCHEGUSBCA12CA2KDM4E
SCHEMBL8591865 0.75 LMNA (0.42) TRIM24TRIM33RAB9ACA12CA2
SCHEMBL8591866 0.75 LMNA (0.42) TRIM24TRIM33RAB9ACA12CA2
SCHEMBL9243593 0.75 ALDH1A1 (0.44) RAB9AKDM4EHPGDCYP3A4TP53
SCHEMBL7574422 0.73 FNTA (0.36) BCHERAB9ACA2KDM4EHPGD
SCHEMBL1079613 0.72 CYP3A4 (0.41) BCHERAB9ACA12CA2KDM4E
SCHEMBL8424497 0.72 BCHE (0.47) BCHEGUSBTRIM24TRIM33RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5873981-A Recovery of anhydrous acids THE DOW CHEMICAL COMPANY (US) 1999-02-23 US claimed
EP-0927148-A3 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION MICHIGAN MOLECULAR INSTITUTE (US) 2002-11-20 EP disclosed
WO-1998011042-A3 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION DOW CHEMICAL CO (US) 2002-10-03 WO disclosed
EP-0927148-B1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION MICHIGAN MOLECULAR INST (US) 2001-03-07 EP disclosed
EP-0949996-A2 LAMINATE STRUCTURES FOR FUEL CONTAINERS THE DOW CHEMICAL COMPANY (US) 1999-10-20 EP disclosed
EP-0948479-A1 RECOVERY OF ANHYDROUS ALKANESULPHONIC ACIDS THE DOW CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
EP-0948479-A1 RECOVERY OF ANHYDROUS ALKANESULPHONIC ACIDS THE DOW CHEMICAL COMPANY (US) 1999-10-13 EP disclosed
EP-0927148-A2 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION THE DOW CHEMICAL COMPANY (US) 1999-07-07 EP disclosed
US-5873981-A Recovery of anhydrous acids THE DOW CHEMICAL COMPANY (US) 1999-02-23 US disclosed
US-5873981-A Recovery of anhydrous acids THE DOW CHEMICAL COMPANY (US) 1999-02-23 US disclosed
WO-1998011042-A2 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION THE DOW CHEMICAL COMPANY (US) 1998-03-19 WO disclosed
US-5723692-A Preparation of 4,4'-dihydroxy-'alkylstiblbene with reduced dimer formation THE DOW CHEMICAL COMPANY (US) 1998-03-03 US disclosed
US-5723692-A Preparation of 4,4'-dihydroxy-'alkylstiblbene with reduced dimer formation THE DOW CHEMICAL COMPANY (US) 1998-03-03 US disclosed
US-5475155-A Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation THE DOW CHEMICAL COMPANY (US) 1995-12-12 US disclosed
WO-1995015301-A1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENES AND 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1995-06-08 WO disclosed
US-5414125-A Epoxy resin curing agent THE DOW CHEMICAL COMPANY (US) 1995-05-09 US disclosed
EP-0579743-A1 DIAMINO-ALPHA-ALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1994-01-26 EP disclosed
US-5268434-A Curable composition THE DOW CHEMICAL COMPANY (US) 1993-12-07 US disclosed
US-5264502-A Curable resins for rod like structure for liquid crystals THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
WO-1992018460-A1 DIAMINO-ALPHA-ALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1992-10-29 WO disclosed