Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.59 |
| ▸ | MMP8 | P22894 | 12/20 | 0.59 |
| ▸ | MMP9 | P14780 | 10/20 | 0.59 |
| ▸ | CCKBR | P32239 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 10/20 | 0.55 |
| ▸ | MMP3 | P08254 | 3/20 | 0.53 |
| ▸ | MMP14 | P50281 | 4/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.50 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | MMP15 | P51511 | 1/20 | 0.50 |
| ▸ | MMP16 | P51512 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.50 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.50 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.50 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242009 | 0.94 | CCKBR (0.56) | MMP2MMP8MMP9CCKBRMMP1 | |
| SCHEMBL8363652 | 0.92 | CCKBR (0.61) | MMP2MMP8MMP9CCKBRMMP1 | |
| SCHEMBL8426512 | 0.88 | MMP2 (0.63) | MMP2MMP8MMP9CCKBRMMP1 | |
| SCHEMBL8363817 | 0.87 | MMP2 (0.62) | MMP2MMP8MMP9CCKBRMMP1 | |
| SCHEMBL8426483 | 0.87 | MMP2 (0.62) | MMP2MMP8MMP9CCKBRMMP1 | |
| SCHEMBL31016495 | 0.87 | CCKBR (0.57) | MMP2MMP8CCKBRMMP1MMP7 | |
| SCHEMBL31016498 | 0.87 | CCKBR (0.57) | MMP2MMP8CCKBRMMP1MMP7 | |
| SCHEMBL31016490 | 0.87 | CCKBR (0.57) | MMP2MMP8CCKBRMMP1MMP7 | |
| SCHEMBL31016497 | 0.87 | CCKBR (0.57) | MMP2MMP8CCKBRMMP1MMP7 | |
| SCHEMBL8426510 | 0.86 | MMP2 (0.62) | MMP2MMP8MMP9CCKBRMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119395-A1 | Novel Depsipeptides and Process for Preparing Same | CUBIST PHARMACEUTICALS, INC. | 2008-05-22 | — | — | US | disclosed |
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | CUBIST PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194714-A1 | Novel depsipeptides and process for preparing same | VIP, DNPEP, PREP | MMP2 1509/4885MMP8 1241/4885MMP9 2211/4885 |
| US-20080119395-A1 | Novel Depsipeptides and Process for Preparing Same | VIP, DNPEP, PREP | MMP2 1509/4885MMP8 1241/4885MMP9 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.