Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859055 | 0.89 | TSHR (0.58) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL2778233 | 0.89 | TSHR (0.58) | TSHRHPGDHCAR2ATMMAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL3421934 | 0.86 | TSHR (0.54) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL3360217 | 0.84 | TSHR (0.55) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL11513248 | 0.84 | TSHR (0.49) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL11665731 | 0.80 | TSHR (0.49) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL10798987 | 0.80 | TSHR (0.48) | TSHRHPGDATMMAPTALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL2032729 | 0.79 | TSHR (0.57) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL3361083 | 0.79 | TSHR (0.61) | TSHRHPGDHCAR2ATMMAPT | |
| SCHEMBL887886 | 0.79 | TSHR (0.61) | TSHRHPGDHCAR2ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5997969-A | Non-allergenic medical and health care devices made from crosslinked synthetic elastomers | DYNAREX CORPORATION | 1999-12-07 | — | — | US | disclosed |