Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | G6PC1 | P35575 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424861 | 1.00 | ALDH1A1 (0.44) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL11179133 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL11179130 | 0.84 | ALDH1A1 (0.44) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL3504061 | 0.83 | CYP1A2 (0.52) | ALDH1A1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL3504060 | 0.83 | CYP1A2 (0.52) | ALDH1A1LMNAMEN1KMT2ATDP1 | |
| SCHEMBL8421139 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL8421140 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL8421148 | 0.81 | CTDSP1 (0.47) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL8421145 | 0.81 | CTDSP1 (0.47) | ALDH1A1LMNAG6PC1MEN1KMT2A | |
| SCHEMBL3650558 | 0.75 | MAPT (0.49) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740654-B1 | MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF | MAYOLY SPINDLER LAB (FR) | 1999-10-13 | — | — | EP | disclosed |
| US-5811456-A | TREATMENT OF ALZHEIMER'S DISEASE | LABORATOIRES MAYOLY SPINDLER (FR) | 1998-09-22 | — | — | US | disclosed |
| EP-0740654-A1 | MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF | LABORATOIRES MAYOLY SPINDLER (FR) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019960-A1 | MONOAMINE OXIDASE B INHIBITORS, PROCESSES FOR THEIR PREPARATION AND USE THEREOF | LABORATOIRES MAYOLY SPINDLER (FR) | 1995-07-27 | — | — | WO | disclosed |