Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650559 | 1.00 | MAPT (0.49) | MAPTKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL3652617 | 0.84 | MAPT (0.47) | MAPTKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL3652618 | 0.84 | MAPT (0.47) | MAPTKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL3504061 | 0.81 | CYP1A2 (0.52) | MAPTKDM4ELMNAL3MBTL1GAA | |
| SCHEMBL3651698 | 0.80 | MAPT (0.45) | MAPTKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL3651696 | 0.80 | MAPT (0.45) | MAPTKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL8424861 | 0.75 | ALDH1A1 (0.44) | LMNAL3MBTL1ALDH1A1MEN1NPC1 | |
| SCHEMBL8424860 | 0.75 | ALDH1A1 (0.44) | LMNAL3MBTL1ALDH1A1MEN1NPC1 | |
| Butanedione SCHEMBL11053048 | 0.72 | CCNB2 (0.62) | MAPTKDM4ECCNB2CDK1CDK4 | |
| SCHEMBL28863987 | 0.72 | RAB9A (0.77) | MAPTKDM4ECCNB2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195029-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | Oryzon Genomics SA (ES) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009027349-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS SA (ES) | 2009-03-05 | — | — | WO | disclosed |