Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.62 |
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | RARG | P13631 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
| ▸ | GOT1 | P17174 | 1/20 | 0.59 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695737 | 0.91 | EPHX2 (0.52) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL4936267 | 0.89 | RARA (0.65) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL6535616 | 0.88 | RARA (0.64) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9453323 | 0.88 | RARA (0.64) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8874310 | 0.87 | RARA (0.62) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL565789 | 0.85 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL1082340 | 0.85 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8424422 | 0.85 | RARA (0.67) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8424419 | 0.84 | RARA (0.46) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124255 | 0.84 | RARA (0.76) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776885-B1 | Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses | CIRD GALDERMA (FR) | 1999-10-27 | — | — | EP | claimed |
| EP-0776885-B1 | Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses | CIRD GALDERMA (FR) | 1999-10-27 | — | — | EP | disclosed |
| EP-0776885-A1 | Diaromatic compounds with an adamantyl group in the ortho position, pharmaceutical and cosmetic compositions containing them and uses | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |