Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 8/20 | 0.77 |
| ▸ | RARB | P10826 | 8/20 | 0.77 |
| ▸ | RARG | P13631 | 8/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.77 |
| ▸ | PGR | P06401 | 1/20 | 0.77 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.77 |
| ▸ | GOT1 | P17174 | 1/20 | 0.77 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082340 | 1.00 | RARA (0.77) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9124255 | 0.99 | RARA (0.76) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL6364425 | 0.92 | RARA (0.71) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8458512 | 0.91 | RARB (0.81) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9124257 | 0.90 | RARA (0.65) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL14027627 | 0.89 | RARB (0.82) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL5078191 | 0.89 | RARA (0.67) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL5366339 | 0.89 | RARA (0.63) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9493164 | 0.89 | RARA (0.63) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL566680 | 0.89 | RARG (0.66) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409728-B1 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0409728-A2 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1991-01-23 | — | — | EP | claimed |
| EP-2740721-B1 | NOVEL BENZOIC ACID AMIDE COMPOUND | AMOREPACIFIC CORP (KR) | 2017-03-22 | — | — | EP | disclosed |
| US-9254251-B2 | Benzoic acid amide compound | AMOREPACIFIC CORPORATION (KR) | 2016-02-09 | — | — | US | disclosed |
| US-9181182-B2 | S1P receptors modulators | AKAAL PHARMA PTY LTD (AU) | 2015-11-10 | — | — | US | disclosed |
| US-20140234241-A1 | NOVEL BENZOIC ACID AMIDE COMPOUND | AMOREPACIFIC CORPORATION (KR) | 2014-08-21 | — | — | US | disclosed |
| EP-2740721-A2 | NOVEL BENZOIC ACID AMIDE COMPOUND | Amorepacific Corporation (KR) | 2014-06-11 | — | — | EP | disclosed |
| US-20120034270-A1 | S1P Receptors Modulators | AKAAL PHARMA PTY LTD (AU) | 2012-02-09 | — | — | US | disclosed |
| EP-2344446-A1 | S1P RECEPTORS MODULATORS | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010095041-A2 | COMPOSITIONS, METHODS, AND KITS FOR TREATING INFLUENZA VIRAL INFECTIONS | EXCRX (SINGAPORE) PTE.LTD. (SG) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010042998-A1 | S1P RECEPTORS MODULATORS | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
| US-5173289-A | Skin disorders, antiinflammatory agents | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1992-12-22 | — | — | US | disclosed |
| US-5059621-A | Treatment of dermatologic ailments linked to keratinization disorder | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1991-10-22 | — | — | US | disclosed |
| US-5015758-A | Process for the preparation of 1-adamantane derivatives | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1991-05-14 | — | — | US | disclosed |
| EP-0409728-A2 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1991-01-23 | — | — | EP | disclosed |
| US-4927928-A | SKIN DISORDERS, EYES, ANTITUMOR | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1990-05-22 | — | — | US | disclosed |
| US-4925658-A | TREATMENT OF DERMATOLOGIC, RHEUMATIC, RESPIRATORY, OPHTHALMOLOGIC DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4920140-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1990-04-24 | — | — | US | disclosed |
| EP-0325540-A1 | Aromatic esters and thioesters, process for their preparation and their use in human or animal therapeutics and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1989-07-26 | — | — | EP | disclosed |
| US-4740519-A | Benzo (b) thiophene carboxylate derivatives and pharmaceutical compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1988-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234241-A1 | NOVEL BENZOIC ACID AMIDE COMPOUND | TYR, AADAC, CUTA | RARA 148/4885RARB 216/4885RARG 185/4885 |
| US-20120034270-A1 | S1P Receptors Modulators | S1PR1, S1PR5, S1PR3 | RARA 4192/4885RARB 3838/4885RARG 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.