Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25057512 | 0.90 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL14596802 | 0.82 | USP2 (0.36) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL21989948 | 0.81 | MEN1 (0.44) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL28847035 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL17260201 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL149832 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL38657276 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL23463369 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL17260206 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL1615056 | 0.80 | LMNA (0.78) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962291-A | MONOCLONAL ANTIBODY CAPABLE OF HYDROLYZING A SUBSTRATE; HAS TWO BINDING SITES: ONE FOR FREE METAL ION, ONE FOR SUBSTRATE | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 1999-10-05 | — | — | US | disclosed |