Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425014 | 0.82 | MEN1 (0.50) | ACE2LMNACYP3A4MEN1KMT2A | |
| SCHEMBL26624481 | 0.81 | LMNA (0.52) | USP2ACE2LMNACYP3A4GPR84 | |
| SCHEMBL26624849 | 0.81 | LMNA (0.52) | USP2ACE2LMNACYP3A4GPR84 | |
| SCHEMBL28742609 | 0.81 | LMNA (0.52) | USP2ACE2LMNACYP3A4GPR84 | |
| SCHEMBL28742731 | 0.81 | LMNA (0.52) | USP2ACE2LMNACYP3A4GPR84 | |
| SCHEMBL26624588 | 0.81 | LMNA (0.52) | USP2ACE2LMNACYP3A4GPR84 | |
| SCHEMBL28318031 | 0.80 | ACE2 (0.55) | USP2ACE2PLA2G2CLMNACYP3A4 | |
| SCHEMBL12047588 | 0.79 | THRB (0.43) | USP2ACE2ACACBACACALMNA | |
| SCHEMBL8896548 | 0.76 | GPR84 (0.42) | ACACBACACALMNAGPR84SPHK1 | |
| SCHEMBL19861238 | 0.75 | USP2 (0.42) | USP2ACACBACACAPLA2G2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007030928-A2 | METHOD FOR THE DIAGNOSIS OF COLORECTAL CANCER AND OVARIAN CANCER BY THE MEASUREMENT OF VITAMIN E-RELATED METABOLITES | PHENOMENOME DISCOVERIES INC. (CA) | 2007-03-22 | — | — | WO | disclosed |