SCHEMBL8425133

SCHEMBL8425133

CC=C(C)C1([SiH2]Cc2ccccc2)CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28178576 0.73 LMNA (0.32) LMNA
SCHEMBL7101828 0.72 MAOA (0.38) LMNA
SCHEMBL7035964 0.71 LMNA (0.30) LMNA
SCHEMBL28187490 0.70
SCHEMBL28348749 0.70
SCHEMBL27836222 0.70
SCHEMBL7035939 0.68
SCHEMBL912666 0.68
SCHEMBL16459656 0.67 KCNH2 (0.36)
Methane SCHEMBL466523 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586276-B1 Index matching compositions with improved DNg/DT MINNESOTA MINING & MFG (US) 1999-10-13 EP disclosed
US-5783115-A CONTAINING DISPERSED SILICA SOL PARTICLES, A LIQUID POLYSILOXANE AND/OR A LIQUID POLYETHER OR COPOLYMER OF BOTH MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-07-21 US disclosed
US-5307438-A Index matching compositions with improved DNG/DT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-04-26 US disclosed
EP-0586276-A2 Index matching compositions with improved DNg/DT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-03-09 EP disclosed