Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15212670 | 0.87 | L3MBTL1 (0.44) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL27754492 | 0.87 | KDM4E (0.53) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL14359917 | 0.86 | KDM4E (0.55) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL3505902 | 0.84 | KDM4E (0.67) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL3551020 | 0.84 | KDM4E (0.50) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL12732387 | 0.84 | ALDH1A1 (0.55) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL1206475 | 0.83 | L3MBTL1 (0.47) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL1019194 | 0.83 | ELANE (0.47) | KDM4EMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL9275434 | 0.83 | KDM4E (0.60) | KDM4EMEN1RECQLKMT2ATHRA | |
| SCHEMBL27491120 | 0.83 | KDM4E (0.49) | KDM4EMEN1RECQLKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946588-A1 | USE OF DIPEPTIDE DERIVATIVES | Astra Aktiebolag (publ) (SE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028327-A1 | NEW USE OF DIPEPTIDE DERIVATIVES | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-07-02 | — | — | WO | disclosed |