Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.33 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425237 | 1.00 | PTK2 (0.36) | PTK2MAPK1NPSR1ALDH1A1MEN1 | |
| SCHEMBL6953602 | 0.95 | PTK2 (0.39) | PTK2MAPK1NPSR1ALDH1A1MEN1 | |
| SCHEMBL6953597 | 0.95 | PTK2 (0.39) | PTK2MAPK1NPSR1ALDH1A1MEN1 | |
| SCHEMBL8423654 | 0.87 | PTK2 (0.38) | PTK2MAPK1NPSR1ALDH1A1KMT2A | |
| SCHEMBL8423653 | 0.87 | PTK2 (0.38) | PTK2MAPK1NPSR1ALDH1A1KMT2A | |
| SCHEMBL8425734 | 0.86 | KMT2A (0.38) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8425736 | 0.86 | KMT2A (0.38) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8425497 | 0.84 | ALDH1A1 (0.35) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8425499 | 0.84 | ALDH1A1 (0.35) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8428139 | 0.83 | KMT2A (0.40) | MAPK1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |