Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423654 | 1.00 | PTK2 (0.38) | PTK2MAPK1NPSR1CD274PDCD1 | |
| SCHEMBL6952724 | 0.95 | PTK2 (0.41) | PTK2MAPK1NPSR1CD274PDCD1 | |
| SCHEMBL6952719 | 0.95 | PTK2 (0.41) | PTK2MAPK1NPSR1CD274PDCD1 | |
| SCHEMBL8425237 | 0.87 | PTK2 (0.36) | PTK2MAPK1NPSR1CD274PDCD1 | |
| SCHEMBL8425239 | 0.87 | PTK2 (0.36) | PTK2MAPK1NPSR1CD274PDCD1 | |
| SCHEMBL8425246 | 0.82 | L3MBTL1 (0.49) | MAPK1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8425249 | 0.82 | L3MBTL1 (0.49) | MAPK1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8425593 | 0.81 | KAT8 (0.40) | MAPK1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL8425597 | 0.81 | KAT8 (0.40) | MAPK1SMN1; SMN2KDM4EMAPTL3MBTL1 | |
| SCHEMBL6953602 | 0.81 | PTK2 (0.39) | PTK2MAPK1NPSR1CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869516-A | 4-(arylaminomethylene)-2,4-dihydro-3-pyrazolones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-02-09 | — | — | US | disclosed |