Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.43 |
| ▸ | MLYCD | O95822 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048720 | 0.90 | MAPK1 (0.43) | PARP10MLYCDNOS1MAPK1SMN1; SMN2 | |
| SCHEMBL17670515 | 0.82 | NPC1 (0.38) | PARP10NOS1SMN1; SMN2ALDH1A1PARP4 | |
| SCHEMBL22241398 | 0.81 | MLYCD (0.41) | MLYCDSMN1; SMN2ALDH1A1EGFRERBB2 | |
| SCHEMBL6698097 | 0.80 | TP53 (0.44) | MLYCDSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL15215895 | 0.79 | POLB (0.49) | MLYCDALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL8016233 | 0.79 | MLYCD (0.40) | MLYCDSMN1; SMN2ALDH1A1EGFRERBB2 | |
| SCHEMBL2069635 | 0.78 | TP53 (0.59) | SMN1; SMN2ALDH1A1CYP2C9KMT2AMEN1 | |
| SCHEMBL22241317 | 0.76 | MLYCD (0.38) | MLYCDSMN1; SMN2ALDH1A1EGFRERBB2 | |
| SCHEMBL22241327 | 0.76 | MLYCD (0.38) | MLYCDSMN1; SMN2ALDH1A1EGFRERBB2 | |
| SCHEMBL5510305 | 0.75 | TP53 (0.40) | MLYCDSMN1; SMN2ALDH1A1CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955506-A | ACETAMIDOBENZAMIDE COMPOUNDS FOR TREATMENT OF PARKINSON'S DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-09-21 | — | — | US | disclosed |