Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8425367 | 0.90 | PARP10 (0.43) | MAPK1MEN1APAF1RGS12HSP90AA1 | |
| SCHEMBL11887705 | 0.85 | ALOX5 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1HDAC6 | |
| SCHEMBL7279376 | 0.83 | CYP3A4 (0.47) | MAPK1NPC1RAB9AEGFRERBB2 | |
| SCHEMBL9614627 | 0.81 | HSD17B3 (0.44) | MAPK1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL817611 | 0.80 | NPC1 (0.59) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17670515 | 0.79 | NPC1 (0.38) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13791624 | 0.79 | NPC1 (0.48) | MAPK1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3930753 | 0.77 | NPC1 (0.50) | MAPK1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL13791114 | 0.77 | RAB9A (0.53) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13791513 | 0.75 | NPC1 (0.55) | NPC1RAB9AALDH1A1MLYCDJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077870-A | ACETAMIDOBENZAMIDE COMPOUNDS EXHIBIT STRONG ACTIVITY AGAINST PARKINSON'S DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-06-20 | — | — | US | disclosed |